Skip to content

Welcome to the Santos Lab!

We are a chemistry lab applying organic synthesis in medicinal chemistry and chemical biology. Central to our work is synthetic methods development and discovery of molecules that improve human health.

Synthetic Methods

Methods that install boron and silicon atoms into carbon-carbon bonds

Mitochondrial Uncouplers 

Small molecule drug discovery program for the  treatment of obesity, fatty liver disease, metabolic diseases, and aging

SphK Inhibitors

Development of sphingosine kinase (SphK) 1 & 2 inhibitors  as medicine for multiple sclerosis, metastatic cancers and kidney fibrosis

S1P Transporters

Medicinal chemistry program to inhibit sphingosine-1-phosphate transport for the treatment of chronic kidney disease and multiple sclerosis


Take a virtual tour of our labs.