8/23/16 Molly Congdon accepted a postdoc position at NIH/NCI with Jeff Gildersleeve. Good luck!

8/19/16 Congrats to Cheryl Peck for receiving a College of Science Doctoral assistantship award!

8/19/16 Dr. Srinath Pashikanti moves to Idaho State University as an assistant professor. Best of luck Sri!

8/17/16 Cheryl's paper is highlighted in organic chemistry portal.

8/17/16 Thanks to NIH/NIGMS for funding our RO1 grant! Cheers to the Santos lab.

8/16/16 Our expert opinion on sphingosine kinase therapeutics is accepted for publication.

7/19/2016 Molly successfully defended her Ph.D. Congrats Dr. Congdon!!!

7/15/2016 Congratulations to Dr. Jessica Wynn for passing her Ph.D. defense with flying colors!

6/2/2016 Jessica's paper on inhibiting HIV-1 replication in cells is accepted in MedChemComm. Fantastic work Jess!

5/25/2016 Astha's chapter on copper-catalyzed organoboron cross-coupling has been accepted. Great job, Astha!

5/3/2016 Congrats to Sri, Joe, Chris, and Matt. Their hydrosilylation of allenes work in water is accepted by Org. Lett.

4/23/2016 Molly received a travel award from the ACS Med Chem division to attend the ACS meeting in Philly this fall. Awesome Molly!

4/22/2016 Amanda and Cheryl's borylation of alkynoates and alkynamides in water is accepted in JOC. Great job to both!

4/22/2016 Congrats to Molly Congdon for winning an outstanding graduate research award!

4/5/16 Undergrad Laura Wonilowicz won a Fralin Summer Fellowship to work in our lab this summer. Well done Laura!

4/4/16 Jessica's paper regarding branched peptide boronic acids is accepted at Bioorganic and Medicinal Chemistry. Great Job!

3/22/16 Beth Childress was selected for a prestigious P.E.O. Scholar Award. Congrats and well done!

3/14/16 Congratulations to Molly! Her sphingosine kinase work is featured on the front cover of ACS. Med. Chem. Lett.

3/1/16 Dr. Astha Verma leaves the lab for a job at KBI Biopharma. Best of luck!

2/15/16 We welcome two first year students: Chris Sibley and Eric Medici.

2/3/16 Molly's naphthalene-based Sphingosine Kinase inhibitors is available online at ACS Med. Chem. Lett. Congrats Molly!

12/7/15 Beth Childress won a CCG Research Excellence Student Travel Award from the Division of Medicinal Chemistry-ACS. Congrats!

11/6/15 Congratulations to Beth Childress and Jessica Wynn for winning awards during VT's Center for Drug Discovery Poster Session!

10/01/15 Prof. Santos is now a fellow of the Institute for Creativity, Arts, and Technology (ICAT).

8/26/15 Congrats to Beth Childress for receiving a College of Science Doctoral assistantship award!

8/4/15 Congrats to Emily, Molly, and team sphingosine kinase for their hard work. The in vivo effects of inhibitors is published in JPET.

7/24/15 Emily Morris recently accepted a teaching position at Manassas Park High School. Woohoo!

7/15/15 Alumni Matthew Nguyen will be attending VCU Medical School this fall. Congrats Matt!

7/1/15 Thanks to ARDRAF for funding our work with sphingosine kinase and Alzheimer's Disease.

6/22/15 Jessica Wynn receives a travel award from the BIOL division of the ACS. Great job!

6/11/15 Joe Calderone's paper dealing with mitochondrial uncouplers for the treatment of diabetes is accepted in BMCL. Congrats!

6/11/15 Fulbright scholar, Amanda Nelson, is highlighed in VT news!

4/28/15 Jessica's review of branched peptide is published in Org. Biomol. Chem. Congrats!

4/25/15 Congratulations to Amanda Nelson for receiving a Fulbright Scholarship! She will be spending a year in Germany with Todd Marder.

3/16/15 Congratulations to Molly on her work with the SAR of sphingosine kinases, which is published in Bioorg. Med. Chem. Lett.!

3/12/15 Cheryl's paper on aqueous borylation of alkynoates is published in Synthesis. Congrats!

3/03/15 Xi and Amanda's paper regarding unsymmetrical diboration is published in ACS Catalysis. Well done!

2/04/15 Neeraj and Emily's selective inhibitors of SphKs is published in J. Med. Chem. Congrats!

1/08/15 Congratulations to Jessica Wynn for receiving a graduate school doctoral assistantship award.

11/20/14 Our review of sphingosine kinases appears in ACS Chemical Biology.

11/6/14 Congratulations to Dr. Xi Guo for passing her dissertation defense. Fantastic job!

10/15/14 Dr. Santos is a recipient of Fralin/ICTAS Innovator's Award from Virginia Tech.

9/30/14 Dr. Santos is named as Cliff and Agnes Faculty Fellow.

8/25/14 Dr. Santos presents at IME Boron Conference in Prague, Czech Republic.

7/16/14 Joe Calderone's Angewandte paper is highlighted in SynFacts. Great job Joe!

6/25/14 Ashley Peralta joins the Santos group.

6/20/14 Jessica Wynn won second prize oral presentation at BORAM XIV, an international meeting of boron chemists. Congrats!

5/17/14 Congratulations to our recent graduates. Dr. Wenyu Zhang will be a postdoc at NIH with Dr. Kuan Wang. Matt Nguyen will be a postbac researcher with Dr. Sidransky at NIH.

4/25/14 Congratulations to the Santos Lab. Award winners from the Chemistry Dept:

Outstanding graduate research: Wenyu Zhang

Outstanding Graduate Teaching Assistant: Molly Congdon

Second Place Poster Winner: Matthew Nguyen

Summer Research: Sean Rafferty

Schug Research Award: Webster Santos












We are interested in using chemistry to understand biological processes. Central to our theme is organic chemistry as a tool that intersects with molecular life sciences such as molecular and cell biology. Our primary focus is the development of chemical toolboxes to address problems in biology. Currently, our work is aimed at the following:



We are grateful for the generous support of our work by:

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