Welcome to the Santos Lab @ Virginia Tech

Save the date: BORAM XVII MEETING at Virginia Tech: June 20-25, 2022

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We are a chemistry lab who apply organic synthesis in medicinal chemistry and chemical biology. Central to our work is synthetic methods development and discovery of molecules that improve human health.

Synthetic Methods

Methods that install boron and silicon atoms into carbon-carbon bonds

Mitochondrial uncouplers 

Small molecule drug discovery program for the  treatment of obesity, fatty liver disease, metabolic diseases, and aging.

SphK inhibitors

Development of sphingosine kinase (SphK) 1 & 2 inhibitors  as medicine for multiple sclerosis, metastatic cancers and kidney fibrosis.


S1P transporters

Medicinal chemistry program to inhibit sphingosine-1-phosphate transport for the treatment of chronic kidney disease and multiple sclerosis. 

Take a virtual tour of our labs.

Recent News (lastest news: click here)